Fig. 4.
Fig. 4. Comparison of the calcium-mobilizing capacity of intact and truncated chemokines on CXCR3-transfected cells. / Met-IP-10 (filled squares), intact (filled symbols), and CD26/DPP IV–truncated (open symbols) IP-10 (diamonds), Mig (circles), and I-TAC (triangles) were tested for their ability to increase the [Ca++]i in CXCR3-transfected CHO cells. Results represent the mean (± SEM) increase of the [Ca++]i of 5 or more independent experiments. The detection limit for the increase of the [Ca++]i is indicated by the dashed line.

Comparison of the calcium-mobilizing capacity of intact and truncated chemokines on CXCR3-transfected cells.

Met-IP-10 (filled squares), intact (filled symbols), and CD26/DPP IV–truncated (open symbols) IP-10 (diamonds), Mig (circles), and I-TAC (triangles) were tested for their ability to increase the [Ca++]i in CXCR3-transfected CHO cells. Results represent the mean (± SEM) increase of the [Ca++]i of 5 or more independent experiments. The detection limit for the increase of the [Ca++]i is indicated by the dashed line.

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