Fig. 4.
Comparison of the calcium-mobilizing capacity of intact and truncated chemokines on CXCR3-transfected cells.
Met-IP-10 (filled squares), intact (filled symbols), and CD26/DPP IV–truncated (open symbols) IP-10 (diamonds), Mig (circles), and I-TAC (triangles) were tested for their ability to increase the [Ca++]i in CXCR3-transfected CHO cells. Results represent the mean (± SEM) increase of the [Ca++]i of 5 or more independent experiments. The detection limit for the increase of the [Ca++]i is indicated by the dashed line.