Time course of the truncation of CXCR3 ligands by CD26/DPP IV.

IP-10 (diamonds), Mig (circles), and I-TAC (triangles) at 5 μM were incubated for different time intervals with 25 U/L soluble CD26/DPP IV as indicated in “Materials and methods.” The remaining concentration of the intact CXCR3 ligands determined by mass spectrometry is indicated in the graphs.