Kinase-dependent transformation.

(A) Western blot of one BCR-FGFR1 clone, 3 ZNF198-FGFR1 clones, and a clone that had been transfected with vector only probed with anti-FGFR1. (B) Proliferation of representative BCR-FGFR1, ZNF198-FGFR1, vector only, and ZNF198-FGFR1/K514R clones in the absence of IL-3.