ICAM-1 expression is lower on various lymph node B-cell subsets in splenectomized animals.

(A) Representative histograms of the ICAM-1 expression for NF (IgM^highCD90^high), ERF (IgM^lowCD90^high), RF (IgM^lowCD90⁻), and MZ (IgM^highCD90⁻) B cells are demonstrated in blood (white) versus lymph node (gray) of normal animals. (B) The ICAM-1 expression of the B-cell subsets in blood and lymph node is depicted for each normal animal. The values for the blood and lymph node of each rat are connected by a line. (C) The ICAM-1 expression of B-cell subsets in lymph node of control and splenectomized animals is shown. The values are given as the mean of the mean fluorescence intensity ± SD (n = 5-6 for each group). The asterisk represents a significant difference (Wilcoxon matched-pairs signed rank test or Mann-Whitney U test; P < .05).