Killing of CD40-activated B cells pulsed with native and heteroclitic peptides.

Cytotoxicity of T-cell lines generated against native and heteroclitic peptides, with killing of CD40-activated autologous B cells pulsed with the peptide at an effector-to-target ratio of 30:1. Results are mean ± SD values from experiments done in triplicate with samples from up to 8 different donors.