Fig. 5.
Effect of PTPεC on IFN-β-induced STAT activation.
(A) M1 stable clones were treated with IFN-β at 1000 U/mL for the times indicated and lysed. STAT1 activation was analyzed as in Figure3, and (B) STAT3 activation was analyzed as in Figure 2. Cells were treated with IFN-β for the times indicated. Total RNA was analyzed for IRF-1 and SOCS-1 expression by Northern blotting. (C) Expression levels of β-actin were also estimated.
