Configuration of the c-myc probes.

(A) Schematic representation of the 2 YAC probes used in this study (figure is not drawn to scale). (B) A typical plasma cell nucleus lacking any c-myctranslocation: both probes are fused on each allele. (C) Plasma cell nucleus showing a c-myc translocation. One allele is normal (represented by the probe fusion), whereas the second allele is translocated: the green probe remained on the der(8), and the red probe was translocated on the partner chromosome.