Survival data of double-positive or selectin double-negative recipients given double-positive or double-negative donor cells.
The first 4 groups of animals (dashed lines: a, b, c, d) received transplants of 5 × 104 BM cells/mouse. Of these, only the group of double-positive animals given double-positive donor cells (group a) survived at the 89% level. The remaining 3 groups of selectin double-negative recipients, 2 receiving either double-positive and one receiving double-negative donor cells died early. An additional 4 groups of animals (A, B, C, D; 5 mice each) received transplants later with 2 × 105 BM cells/mouse. These 4 groups survived beyond 30 days. The following combinations were used: A and a: double-positive cells to double-positive recipients; B and b: double-negative cells to double-positive recipients; C and c: double-positive cells to double-negative recipients; and D and d: double-negative cells to double-negative recipients.
