Loss of blood DCs with disease progression in patients with HIV-1 infection.

(A-D) Loss of DCs with increasing RNA viral load. (A) Total number of DCs in blood. (B) Percentage of DCs in the PBMC population. (C) Number of pcDCs/mL. (D) Number of myDCs/mL. (E) Loss of pcDCs and (F) myDCs with decreasing CD4 count. In panels A-D, data points to the left of the break in the x axis show results in uninfected controls.