MSCs isolated and cultured in the first trimester.

A-D, fetal blood (9⁺² weeks); E-H, fetal liver (10⁺² weeks); and I-L, fetal bone marrow (11⁺²weeks. Cytospins of uncultured fetal blood (A), fetal liver (E), and fetal bone marrow (I) were stained with Leishman stain (× 1000 magnification). Three- and 8-day culture of a mesenchymal colony from fetal blood (B-C), fetal liver (F-G), and bone marrow (J-K) were stained with crystal violet (× 400 and × 100 magnification, respectively). Cytospins of a trypsinized MSC colony from fetal blood (D), fetal liver (H), and fetal bone marrow (L) were stained with Leishman stain (× 1000 magnification).