Fig. 5.
MG-132 induces apoptosis in primitve AML cells.
MG-132 induces potent apoptosis in primitive AML cells (specimen 7 in Table 1). Annexin V/7-AAD profiles of total AML (left panels) and CD34+/CD38− cells (right panels) treated with 100 μg/mL Ara-C (top panels) or 1 μM MG-132 (bottom panels).