Fig. 3.
Fig. 3. Cytology of the bone marrow in TTP/TNFR-deficient mice. / Bone marrow was flushed from the femurs of adult mice, and cytopreparations were stained with a modified May-Grünwald-Giemsa stain. Magnification was × 100. In both the WT and TNFR1/2KO mice, the marrow contains a normal mixture of cells of the myeloid, erythroid, and lymphoid lineages. However, in the TTP-deficient cells, regardless of the presence or absence of TNF-α receptors (TTPKO, TTP/TNFR1KO, TTP/TNFR2KO, or 3KO), the marrow cellularity appears to be strikingly shifted to the myeloid lineage.

Cytology of the bone marrow in TTP/TNFR-deficient mice.

Bone marrow was flushed from the femurs of adult mice, and cytopreparations were stained with a modified May-Grünwald-Giemsa stain. Magnification was × 100. In both the WT and TNFR1/2KO mice, the marrow contains a normal mixture of cells of the myeloid, erythroid, and lymphoid lineages. However, in the TTP-deficient cells, regardless of the presence or absence of TNF-α receptors (TTPKO, TTP/TNFR1KO, TTP/TNFR2KO, or 3KO), the marrow cellularity appears to be strikingly shifted to the myeloid lineage.

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