Increasing donor age reduced survival for both HLA-matched and HLA-mismatched transplants.

HLA-matched donors aged 18 to 30 years were associated with the greatest survival of recipients. Survival results in HLA-mismatched donors aged 18 to 30 years were similar to those in HLA-matched donors aged 46 years or older. The poorest survival was observed with HLA-mismatched donors older than 46 years.