Fig. 3.
Fig. 3. Reactivity of PA autoantibodies with GPIIbD163A-IIIa. / Eluates from patients 1, 3, and 8, with impaired binding to KO variant GPIIb-IIIa, showed the impaired binding to GPIIbD163A-IIIa. Results are expressed as ΔOD: [OD value obtained from a test sample − (mean + 3 SD) OD value obtained from 5 control samples]. Open columns represent ΔOD value in antigen-capture ELISA using WT GPIIb-IIIa, and filled columns represent ΔOD value in antigen-capture ELISA using GPIIbD163A-IIIa.

Reactivity of PA autoantibodies with GPIIbD163A-IIIa.

Eluates from patients 1, 3, and 8, with impaired binding to KO variant GPIIb-IIIa, showed the impaired binding to GPIIbD163A-IIIa. Results are expressed as ΔOD: [OD value obtained from a test sample − (mean + 3 SD) OD value obtained from 5 control samples]. Open columns represent ΔOD value in antigen-capture ELISA using WT GPIIb-IIIa, and filled columns represent ΔOD value in antigen-capture ELISA using GPIIbD163A-IIIa.

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