Fig. 9.
Fig. 9. Interaction of DP1 and DP2receptors in regulating eosinophil responses. / Stimulation of DP2 receptors by PGD2 leads to activation of eosinophils (CD11b expression), which is attenuated by simultaneous activation of DP1 receptors. Blockade of DP1 receptors with BWA868C removes this inhibitory effect and enhances PGD2-induced eosinophil activation.

Interaction of DP1 and DP2receptors in regulating eosinophil responses.

Stimulation of DP2 receptors by PGD2 leads to activation of eosinophils (CD11b expression), which is attenuated by simultaneous activation of DP1 receptors. Blockade of DP1 receptors with BWA868C removes this inhibitory effect and enhances PGD2-induced eosinophil activation.

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