CX3CR1 function and HIV viremia.

FKN-induced actin polymerization was evaluated in CD45RO⁺(A,B) and CD45RO⁻ (C,D) Th lymphocytes from HIV-infected patients. The kinetics of actin polymerization (A,C) was compared between 20 patients and 18 patients with HIV RNA counts below (full symbols) and above (empty symbols) 10 000 copies per milliliter, respectively. Actin polymerization 15 seconds after FKN addition (B,D) was compared between patients treated or not treated with ARV drugs. VL indicates viral load (HIV copies/mL). *P = .05; **P = .005, t test.