LPS induction of the Egr-1 promoter is mediated by SRE3, SRE4, and SRE5.

(A) LPS induction of a 5′ deletion series of the Egr-1 promoter. (B) LPS induction of the wild-type Egr-1 promoter and mutants of SRE3, SRE4, and SRE5. Luciferase activity in cell lysates was determined, and results were expressed as fold induction. Data (mean ± SD) are shown for 3 independent experiments.