Frequency of EBV-infected cells in EBV-seropositive normal individuals and patients with acute IM, EBV-HLH, and CAEBV.

The frequency of EBV-infected cells in PBMNCs from EBV-seropositive normal subjects and patients with acute phase of IM, CAEBV, and EBV-HLH were estimated by the EBER-1 ISH as described. The closed circles indicate the data of each sample and the open circles and vertical bars represent the logarithmic mean and SD of each disease category. *P < .001, #P < .005, andP < .05 represent the significance estimated by the Mann-WhitneyU test.