Perforin-dependent cytotoxicity mediated by bcr-abl–specific CD4⁺ T-lymphocyte clones.

(A) Effect of EGTA on cytotoxicity mediated by MY-1 and TO-1 against b3a2 peptide–loaded autologous mature DCs was determined at an effector:target cell ratio of 5:1. (B) Effect of CMA on cytotoxicity mediated by MY-1 and TO-1 against b3a2 peptide–loaded autologous mature DCs was determined at an effector:target cell ratio of 5:1.