American Society of Hematology

Fig. 7.

$Fig. 7. Bcr-Abl+ cells adherent to fibronectin do not accumulate cytochrome c in the cytoplasm following γ-irradiation. / Bcr-Abl+ BaF3p185 were cultured in the presence or absence of STI571/IL-3 overnight in serum-free medium on fibronectin or polylysin. Nonadherent cells were removed, selectively adherent cells were γ-irradiated with 0, 8, or 50 Gy as indicated. After a growing period of 17 hours, Western blot analysis of cytochrome c in the cytoplasmic fraction (5 μg/lane) was performed.$

Bcr-Abl⁺ cells adherent to fibronectin do not accumulate cytochrome c in the cytoplasm following γ-irradiation.

Bcr-Abl⁺ BaF3p185 were cultured in the presence or absence of STI571/IL-3 overnight in serum-free medium on fibronectin or polylysin. Nonadherent cells were removed, selectively adherent cells were γ-irradiated with 0, 8, or 50 Gy as indicated. After a growing period of 17 hours, Western blot analysis of cytochrome c in the cytoplasmic fraction (5 μg/lane) was performed.

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