Fig. 3.
Anti–Thy-1 inhibits IL-2–induced proliferation but not cell survival.
(A) GPI+ 2.10 T cells were cultured in the presence of immobilized anti–Thy-1 or an mAb isotype control, in the presence or absence of 15 U/mL IL-2. After 20 hours, the viability of cells in each condition was assessed by flow cytometry. (B) 3H-thymidine uptake in response to 15 U/mL IL-2 was assessed in cultures set up in parallel to those in panel A.