Analysis of Ph⁺ metaphase cells with or without a deletion of the derivative chromosome 9 using the triple-probe or D-FISH systems.

Each panel shows a cartoon of the expected hybridization signals together with a partial metaphase. Using the triple-probe system (A,B), a blue signal is absent from the derivative chromosome 9 (der 9) in a cell carrying a deletion of that chromosome (B). Using the D-FISH system (C,D), note the absence of the colocalized red/green signal on the derivative chromosome 9 in a cell carrying a deletion of that chromosome (D).