Fig. 1.
Intraperitoneal injection antiplatelet mAb.
The role of Fcγ receptors in antibody-induced thrombocytopenia after intraperitoneal injection of 5 μg of antiplatelet mAb MWReg30. Time-course of mean platelet counts (± SEM, n = 6) is shown after injection of MWReg30 at t = 0 minute. Mice were pretreated with 2.4G2 (▪, 5 μg/g intravenously), CoVF(▴), or saline (■), before MWReg30. Baseline platelet numbers were 6.37 ± 0.32 × 108/mL blood. Results are expressed as the mean of 3 experiments ± SEM. Asterisks indicate statistically significant differences compared to saline control (*P < .05; **P < .01).
