Dose dependency of apoptosis in response to IFN-α plus LPS or LTA.

IFN-α and LPS (A) or LTA (B) was added at the indicated concentrations alone (▴) or together with 10 U/mL (●), 100 U/mL (♦), or 1000 U/mL IFN-α (▪) on day 0 to cultures of monocytes supplemented with IL-4 and GM-CSF. The induction of apoptosis was quantified by FACS analysis on day 6 as detailed in Figure1.