Fig. 3.
NAC attenuates As2O3-mediated cell death.
Cells (2.5 × 105) were cultured in the absence (■) or the presence of As2O3 (2 μM; ░) or As2O3 (2 μM) and NAC (10 μM; ▪) for 48 hours. Viability was assessed by Annexin V–FITC and PI staining followed by FACScan analysis. Data are presented as the mean ± SD of at least 3 independent experiments per cell line. *Means of the As-treated cells are significantly lower than those of the As+NAC–treated cells and the control cells (P < .005). **Means of the As-treated cells are lower than those of the As+NAC–treated cells (P < .03) and the control cells (P < .005). #Means of the As+NAC–treated cells are lower than those of the control cells (P < .01).
