Fig. 4.
Fig. 4. Immunophenotypic and cytolytic profile of pp65495-503-specific CTL line. / This line killed (A) autologous PHA-blasts pulsed with pp65495-503 (▪) and (B) the CMV infected HLA-*A0201+ MRC5 fibroblast cell line (▪). There is little or no killing of autologous PHA-blasts pulsed with the human papillomavirus-derived peptide E711-20 (♦, A), K562 cells (●), and noninfected MRC5 fibroblasts (♦, B). The pp65495-503-specific CTL line is predominantly CD8+ and stains intensely with HLA-*A0201/pp65495-503 tetramer (C).

Immunophenotypic and cytolytic profile of pp65495-503-specific CTL line.

This line killed (A) autologous PHA-blasts pulsed with pp65495-503 (▪) and (B) the CMV infected HLA-*A0201+ MRC5 fibroblast cell line (▪). There is little or no killing of autologous PHA-blasts pulsed with the human papillomavirus-derived peptide E711-20 (♦, A), K562 cells (●), and noninfected MRC5 fibroblasts (♦, B). The pp65495-503-specific CTL line is predominantly CD8+ and stains intensely with HLA-*A0201/pp65495-503 tetramer (C).

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