Fig. 8.
Fig. 8. Effect of gamma irradiation on the immune tolerance induced by transfusions of UV-B–irradiated leukocytes. / Tolerant and naive CBA mice were irradiated with 0, 1, 2, or 4 Gy gamma irradiation and challenged with 2 weekly intravenous infusions of a full immunogenic dose (2 × 105) of BALB/c PBMCs. The development of anti–H-2d antibody activities was measured by immunofluorescence flow cytometry. Broken line indicates the cutoff value for positive antibody detection.

Effect of gamma irradiation on the immune tolerance induced by transfusions of UV-B–irradiated leukocytes.

Tolerant and naive CBA mice were irradiated with 0, 1, 2, or 4 Gy gamma irradiation and challenged with 2 weekly intravenous infusions of a full immunogenic dose (2 × 105) of BALB/c PBMCs. The development of anti–H-2d antibody activities was measured by immunofluorescence flow cytometry. Broken line indicates the cutoff value for positive antibody detection.

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