Inhibition of migration to SCF of transfectants.

The effect of tyrosine kinase inhibitors expressed both as percent migration and percent inhibition (A) Genistein (1-100 μM) and (B) Tyrphostin AG1296 (1-100 μM) on cell migration to SCF (10 ng/mL) in D816V (▪), and wild-type Kit transfectants (■). Data are presented as mean ± SEM (n = 2). When error bars are not shown, the SEM was too small to be diagrammed. Asterisks represent values that were significant at P ≤ .05.