Chemotaxis responses of transfectants.

The cell migration of wild-type kit (●), D816V (♦), and pcDNA-3 (vector alone) transfectants (▪) to (A) stem cell factor (SCF) and (B) stromal cell derived factor 1-α (SDF-1α). Data are presented as mean ± SEM (n = 3). Asterisks in panel A represent values that were significant at P ≤ .05 when migration of D816V and wild-type Kit transfectants were compared. (C) Comparison of chemokinesis in D816V (▪), wild-type Kit (■), and pcDNA-3 transfectants (▧). Data are presented as mean ± SEM (n = 2).