Fig. 6.
Antibody 1B5 prolongs the time to occlusive thrombus formation in carotid arteries of wild-type mice.
Antibodies (2 mg/kg) were administered by intraperitoneal injection within 1 hour before arterial injury. Time to maximal temperature reduction occurred 8 minutes and 18.5 minutes after the initiation of injury in mice treated with control F (ab′)2 and 1B5 Fab, respectively. No temperature reduction occurred in the mouse treated with 1B5 F(ab′)2 for up to 30 minutes after the application of FeCl3.
