Correlation between biomaterial-mediated inflammatory responses and fibrinogen P1/P2 epitope exposure.

The numbers of implant-associated phagocytes (both Mφs and PMNs) are graphed against the measurement of the exposure of P1 (panel A) and P2 (panel B) epitopes. The correlations between P1/P2 exposure and inflammatory responses are significant at P < .05 in both cases.