Fig. 4.
![Fig. 4. Functional responses after IL-12 stimulation of cytokine-primed T cells. / Activated T cells were primed with or without cytokines as indicated for 2 days. These cells were then washed and treated with or without IL-12 for 2 days. IFN-γ produced by activated cells was quantified by ELISA (A). All values represent net IFN-γ production measured by the difference between levels produced in the presence and absence of IL-12. T-cell proliferation (B) was quantified by measuring the incorporation of [3H]TdR. The fold proliferation compares values in T cells treated with IL-12 versus T cells without additional IL-12.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/97/12/10.1182_blood.v97.12.3860/6/h81211192004.jpeg?Expires=1724157686&Signature=VNxlP8b~KnbFOQRHfHMxgqE27DAjaZz2cspYxhs9mtnuN0AMXpu4PNuV1-tl5-DajHUNAdbVWb4Gb-KtCzbJe7eRoikAyXn4CJWdw70zQrG8sNYfM3u7XfW~SePruyfzjr9yTBllqaFbFXGvBpv3ybAr2uAKaGUew0Th29vRBV4-0TxsFNfq6cR7qYvM5EdKOjsAucA6h-qwLx4TTElNgWF3kzLQTTxrL5uCC1pVUm05n5~IWqrjX2qCIJu7PfBJ1KcyC0F0uvClP43bn3z2wswD0Ug0o0BGf5cdxLt8FDoTWkjyPM-svyeVzBEKLkt3TG4zB1rXLsOnhvDthutfAQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Functional responses after IL-12 stimulation of cytokine-primed T cells.
Activated T cells were primed with or without cytokines as indicated for 2 days. These cells were then washed and treated with or without IL-12 for 2 days. IFN-γ produced by activated cells was quantified by ELISA (A). All values represent net IFN-γ production measured by the difference between levels produced in the presence and absence of IL-12. T-cell proliferation (B) was quantified by measuring the incorporation of [3H]TdR. The fold proliferation compares values in T cells treated with IL-12 versus T cells without additional IL-12.
