Surface-bound TFPI-1 inhibits TF activity on mononuclear cells after AMI.

TFPI-1–dependent inhibition of TF function 96 hours after stenting in patients with AMI or stable angina. FXa generation of mononuclear cells was measured in the presence and absence of anti–TFPI-1 antibody after the addition of factors VIIa and X. Values are expressed as mean ± SEM. *P = .001 compared to the values without anti-TFPI. †P = .04 compared to the patients with stable angina.