Fig. 5.
Fig. 5. Human dimeric and monomeric forms of erythropoietin have the same pharmacokinetics in vivo. / Six groups of 3 C57BL/6 mice were injected intravenously (A), intraperitoneally (B), or subcutaneously (C) with 200 U/kg (as determined by proliferation assay) hEpoM (diamonds) or hEpoD (circles). Erythropoietin production is given as the percentage of the maximum erythropoietin level observed 15 minutes after intravenous injection, 1 hour after intraperitoneal injection, and 2 hours after subcutaneous injection.

Human dimeric and monomeric forms of erythropoietin have the same pharmacokinetics in vivo.

Six groups of 3 C57BL/6 mice were injected intravenously (A), intraperitoneally (B), or subcutaneously (C) with 200 U/kg (as determined by proliferation assay) hEpoM (diamonds) or hEpoD (circles). Erythropoietin production is given as the percentage of the maximum erythropoietin level observed 15 minutes after intravenous injection, 1 hour after intraperitoneal injection, and 2 hours after subcutaneous injection.

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