Fig. 3.
De novo erythropoiesis occurs in the spleen of anti-CD147–treated mice.
DBA2 mice were injected intraperitoneally with 100 μg RL73 F(ab′)2 or Ter119 F(ab′)2 and killed at the indicated time points. (A) Spleen cells were stained for expression of Ter119 and VLA-4 and analyzed by FACS on day 3. (B) Kinetics of the increase in percentage of Ter119+, VLA-4+ cells in spleen of mice treated with 100 μg RL73 F(ab′)2 (▪) or Ter119 F(ab′)2 (●).
