Fig. 2.
![Fig. 2. Effect of IDV on lymphoproliferation. / PBMCs from healthy volunteers were preincubated without or with different concentrations of IDV for 18 hours followed by activation with different stimuli for an additional 48 hours. Proliferation was measured with [14C]-thymidine incorporation added at 1 μCi/well for the last 48 hours. Results of [14C]-thymidine incorporation in IDV-treated cultures are expressed as the percentage of responses of cells cultured without IDV. Data represents mean ± SD for 1 of 5 representative experiments: ♦, medium alone; ●, anti-CD3 (0.5 μg/mL); ▴, PHA (2 μg/mL); ▪, PMA (10 ng/mL); + Ionomycin (1 μM); and ○, Con A (2 μg/mL).](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/98/2/10.1182_blood.v98.2.383/5/h81411295002.jpeg?Expires=1724272608&Signature=n-h3a-oNktNqSq8MnAkwr9q6WpZvpSiTAUwB~hIF3CDTmDCCAu94ux1TRK958Vc1LOOMTTTGu8XX~CSg7ZmXDBwWzB60UwKOKMfEU9y3DU457Rnq604o~-kCGKHyMjTX2Z6ZRzCBB~Gx7bY09qhXJgmsNDnoE8lzf92qV50ZBmy88TEWs3P7UGPj9FWo71W8EH9UBOAgve0tnaanv~sKnI-lknaprzzoTOQh5b1H871ritAXPI4O86GvH54zZYAC4DIA8vlRFhjTAIilxc-4yAmiLoyoBPU8WQ8Km8skBoKxXU6YvgTcerQqFzrkGut1iiovec51tcG3qX0MCSGOQA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Effect of IDV on lymphoproliferation.
PBMCs from healthy volunteers were preincubated without or with different concentrations of IDV for 18 hours followed by activation with different stimuli for an additional 48 hours. Proliferation was measured with [14C]-thymidine incorporation added at 1 μCi/well for the last 48 hours. Results of [14C]-thymidine incorporation in IDV-treated cultures are expressed as the percentage of responses of cells cultured without IDV. Data represents mean ± SD for 1 of 5 representative experiments: ♦, medium alone; ●, anti-CD3 (0.5 μg/mL); ▴, PHA (2 μg/mL); ▪, PMA (10 ng/mL); + Ionomycin (1 μM); and ○, Con A (2 μg/mL).
