Fig. 7.
Fig. 7. The gingipains induce responses in PAR-4–transfected cells. / Increase in intracellular calcium levels in N1LF PAR-4 cells following treatment with (A) 25 nM thrombin, (C) 4.5 nM HRgpA, or (E) 18 nM RgpB. N1LF cells were treated with (B) 25 nM thrombin, (D) 18 nM HRgpA, or (F) 18 nM RgpB, followed by treatment with 1 μM bradykinin. The traces are representative of 3 observed.

The gingipains induce responses in PAR-4–transfected cells.

Increase in intracellular calcium levels in N1LF PAR-4 cells following treatment with (A) 25 nM thrombin, (C) 4.5 nM HRgpA, or (E) 18 nM RgpB. N1LF cells were treated with (B) 25 nM thrombin, (D) 18 nM HRgpA, or (F) 18 nM RgpB, followed by treatment with 1 μM bradykinin. The traces are representative of 3 observed.

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