Fig. 3.
Fig. 3. Effects of desensitization of [Ca++]i responses in platelets. / Cells were exposed to: (A) 1 nM, 25 nM, or 100 nM thrombin followed by 0.5 nM HRgpA; (B) 0.05 nM, 0.1 nM, or 1 nM HRgpA followed by 42 nM thrombin. The results shown represent the desensitization effects for 1 of the 4 donors in which these effects were observed.

Effects of desensitization of [Ca++]i responses in platelets.

Cells were exposed to: (A) 1 nM, 25 nM, or 100 nM thrombin followed by 0.5 nM HRgpA; (B) 0.05 nM, 0.1 nM, or 1 nM HRgpA followed by 42 nM thrombin. The results shown represent the desensitization effects for 1 of the 4 donors in which these effects were observed.

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