Fig. 3.
Effects of desensitization of [Ca++]i responses in platelets.
Cells were exposed to: (A) 1 nM, 25 nM, or 100 nM thrombin followed by 0.5 nM HRgpA; (B) 0.05 nM, 0.1 nM, or 1 nM HRgpA followed by 42 nM thrombin. The results shown represent the desensitization effects for 1 of the 4 donors in which these effects were observed.