Fig. 1.
![Fig. 1. The [Ca++]i response of platelets to different concentrations of HRgpA, RgpB, and thrombin. / Platelets from 2 donors were loaded with Fura-2 and stimulated with HRgpA, RgpB, and thrombin. The responses in one donor to HRgpA (A) and thrombin (B) and in another donor to RgpB (C) and HRgpA (D) are shown. The [Ca++]i increases at different concentrations represent the mean from 3 traces similar to those shown in Figure 2, yielding a curve that could be fitted by an equation for single site binding and generate an EC50 value with associated estimate of the SE.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/97/12/10.1182_blood.v97.12.3790/6/h81211171001.jpeg?Expires=1726834576&Signature=1D4tnX4gZz4YeM68SSmXDy24jvOjDvtmHom9D8vjvQfFZaa46lgyPohDizZQyiCNmlT2BBBJdmTP88hVr3Bcdtge5cWYdHXAMZrocwgx3v595Sqnv6ts5h-5laLbWCzmt4zASxcAiZlEpIhp8GaXi-~y60SLFzmjQ-V4v4Lo~O8soaqQZO6kmhOM1W7t-l~ohBjBe7dcA-f~kiwkw3-dFvJ8cbhpSn-LB2rKFT-RcO61mCY0ySdCEr5YKO6PS~OtC9Frkzo1127GpZD0njd3ctIUQAEvKWxoQT0-tRtjFAOYMB7Wvgwx9omlH0qotaYBq3busHM4~JHeWL7Gw26LOA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
The [Ca++]i response of platelets to different concentrations of HRgpA, RgpB, and thrombin.
Platelets from 2 donors were loaded with Fura-2 and stimulated with HRgpA, RgpB, and thrombin. The responses in one donor to HRgpA (A) and thrombin (B) and in another donor to RgpB (C) and HRgpA (D) are shown. The [Ca++]i increases at different concentrations represent the mean from 3 traces similar to those shown in Figure 2, yielding a curve that could be fitted by an equation for single site binding and generate an EC50 value with associated estimate of the SE.
