Fig. 4.
Fig. 4. JAQ1-mediated potentiation of ADP-induced activation is independent of P2Y1 or Gαq. / Washed platelets from wild-type (WT), P2Y1-deficient (P2Y1−/−), or Gαq-deficient (Gαq−/−) mice were activated with ADP (5 or 100 μM) in the presence or absence of JAQ1 (10 μg/mL). Shape change was blocked in P2Y1- and Gαq-deficient mice.

JAQ1-mediated potentiation of ADP-induced activation is independent of P2Y1 or Gαq.

Washed platelets from wild-type (WT), P2Y1-deficient (P2Y1−/−), or Gαq-deficient (Gαq−/−) mice were activated with ADP (5 or 100 μM) in the presence or absence of JAQ1 (10 μg/mL). Shape change was blocked in P2Y1- and Gαq-deficient mice.

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