Platelet glycoprotein expression analysis in whole blood.

(A) An antibody (perCP labeled) against GPIIIa was used to identify platelets in blood samples. The platelets of patient V:3 are at least 4 to 5 times larger than control platelets (localized in the normal platelet population, shown in the red ellipses). A platelet subpopulation was observed (shown in blue circles) consisting of 1:1 platelet red blood cell conjugates. (B) Bars showing the normalized expression of GPIbα and GPIbβ in the 2 platelet populations (red versus blue). No abnormalities were seen for the carriers VI:5 and IV:1.