Fig. 5.
Treatment of patient PBMCs with Thal and IMiDs triggers increased lysis of autologous MM cells.
PBMCs from 2 patients with MM were cultured with IL-2 for 72 hours, and then by 1 μg/mL Thal/IMiDs daily for 72 hours. Lysis of autologous MM cells by these cells was measured in a standard 51Cr release assay at a 30:1 effector-target ratio.
