FISH analysis of

p53 gene copy number in SLVL. Double-color FISH analysis using a probe for chromosome 17 centromere (green signal) and locus-specific probe for p53 (red signal) allowing for identification of cases with one signal for the p53 probe due to monosomy 17. (A) Normal control showing 2 signals for centromere 17 and 2 signals for p53. (B) A patient with hemizygous deletion of p53 (2 green and 1 red signals).