Fig. 7.
Fig. 7. In vivo clearance of 6-19J and L8D IgG3 mAbs. / Half a milligram each mAb (○, 6-19J; ●, L8D) was injected intravenously into immunoglobulin-deficient μMT mice (3 mice per group). Blood samples were collected at the time points indicated. The amount of each mAb remaining in blood was calculated relative to the value 1 minute after the injection. Error bars (± 1 SD) are shown only on last points; fractional errors of other points are similar or lower.

In vivo clearance of 6-19J and L8D IgG3 mAbs.

Half a milligram each mAb (○, 6-19J; ●, L8D) was injected intravenously into immunoglobulin-deficient μMT mice (3 mice per group). Blood samples were collected at the time points indicated. The amount of each mAb remaining in blood was calculated relative to the value 1 minute after the injection. Error bars (± 1 SD) are shown only on last points; fractional errors of other points are similar or lower.

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