Fig. 4.
The distribution of serum IL-10 protein concentration per unit of PBMC mRNA plotted against the log of relative IL-10 mRNA level.

The distribution of serum IL-10 protein concentration per unit of PBMC mRNA plotted against the log of relative IL-10 mRNA level.

The ALPS patients (▪ ; fitted by a light linear regression line) can be seen to produce more protein per unit of IL-10 mRNA than do the healthy subjects (●; heavier regression line). Healthy relatives who had Fas mutations show slightly more IL-10 protein per unit of RNA (■; dashed regression line) than did healthy, unrelated controls.

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