Osteoclast precursors express MIP-1α receptors.

Isolated human bone marrow and CFU-GM–derived cells were prepared and subjected to RT-PCR analysis for CCR1 and CCR5 expression. Human bone marrow (HBM) and CFU-GM–derived cells both expressed CCR1 and CCR5. Human marrow stromal cells (PSV10) only expressed the CCR5 receptor in low concentrations. Controls for these experiments were expression of GAPDH messenger RNA.