Fig. 2.
Fig. 2. Dose-dependent stimulatory effect of anti-CD11b and anti-CD11c mAbs and sCD23 chimeric proteins on the steady-state level of MIP-1α and MIP-1β mRNAs. / Monocytes (7 × 106 cells) were left untreated or incubated for 1 hour with various concentrations of the following effectors: anti-CD11b (ICRF44; A), anti-CD11c (BU15; B), ZZ-CD23 (C), and MBP-CD23 (D). RNA was isolated and analyzed for expression of MIP-1α, MIP-1β, IL-8, and GAPDH mRNAs. Results are representative of 2 distinct experiments.

Dose-dependent stimulatory effect of anti-CD11b and anti-CD11c mAbs and sCD23 chimeric proteins on the steady-state level of MIP-1α and MIP-1β mRNAs.

Monocytes (7 × 106 cells) were left untreated or incubated for 1 hour with various concentrations of the following effectors: anti-CD11b (ICRF44; A), anti-CD11c (BU15; B), ZZ-CD23 (C), and MBP-CD23 (D). RNA was isolated and analyzed for expression of MIP-1α, MIP-1β, IL-8, and GAPDH mRNAs. Results are representative of 2 distinct experiments.

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