Fig. 2.
![Fig. 2. Fever-range WBH stimulates lymphocyte adhesion to PNAd and MAdCAM-1 on HEV. / Splenic lymphocytes were isolated from BALB/c mice treated for 6 hours with WBH and from normothermic mice. The cells were then tested for adhesion to PLN and PP HEV (tissues from non–heat-treated mice) in a frozen-section adhesion assay under mechanical shear conditions. The specificity of lymphocyte-HEV adhesion was determined using the indicated function-blocking mAbs. Values represent the mean ± SE of 3 independent experiments. The differences between adhesion of splenocytes from normothermic control mice and WBH-treated mice were significant (P < .0001 [*] by unpaired 2-tailed Studentt test).](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/97/9/10.1182_blood.v97.9.2727/6/h80910963002.jpeg?Expires=1722680112&Signature=FyVPz6HUyv6NLY8S4BZtdjVeGmW4l-8wTwQcSWoNNKxACQ9TbzpyNOZF-2CalR5hCV7GeMYsz0HL3o528MSdwVQiQCVnsUHKu-FgBvzQ38r9NDNbjZxQS-x0iCT6rljrL1q3VMFxxLqyuUcYaEHmze2OxE-ukaQDPONIDEcoVWwwvEttxPHFgdJyT3ilHgdborHHqF08GMzq8XyulyhAGb8K9l0Smqw7Huc0pwdUEu601HSNKCJz2cQXP6utHHC2JIuq0mLushMlKdxyysfuUH6FSS4eeJFJFDtFjhY7XQ3w2w7yRNksFvl9sfXxJIgVABVlRTkj8~EwCQHCZxJyeQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Fever-range WBH stimulates lymphocyte adhesion to PNAd and MAdCAM-1 on HEV.
Splenic lymphocytes were isolated from BALB/c mice treated for 6 hours with WBH and from normothermic mice. The cells were then tested for adhesion to PLN and PP HEV (tissues from non–heat-treated mice) in a frozen-section adhesion assay under mechanical shear conditions. The specificity of lymphocyte-HEV adhesion was determined using the indicated function-blocking mAbs. Values represent the mean ± SE of 3 independent experiments. The differences between adhesion of splenocytes from normothermic control mice and WBH-treated mice were significant (P < .0001 [*] by unpaired 2-tailed Studentt test).
