Fig. 1.
Fig. 1. Fever-range WBH causes lymphocyte redistribution in lymphoid tissues. / After WBH treatment of BALB/c mice for 6 hours (core temperature, 39.8 ± 0.2°C), the total number of lymphocytes in lymphoid organs (peripheral blood [PB], PLN, and spleen) was quantified. L-selectin and α4β7 integrin expression on tissue lymphocytes was analyzed by flow cytometry. Values represent the mean ± SE of 3 independent experiments. Analysis by unpaired 2-tailed Student t test showed that the difference between the number of lymphocytes in PB and PLN of normothermic controls (37.1 ± 0.2°C) and WBH-treated mice was significant (* indicates P < .02 and **,P < .03).

Fever-range WBH causes lymphocyte redistribution in lymphoid tissues.

After WBH treatment of BALB/c mice for 6 hours (core temperature, 39.8 ± 0.2°C), the total number of lymphocytes in lymphoid organs (peripheral blood [PB], PLN, and spleen) was quantified. L-selectin and α4β7 integrin expression on tissue lymphocytes was analyzed by flow cytometry. Values represent the mean ± SE of 3 independent experiments. Analysis by unpaired 2-tailed Student t test showed that the difference between the number of lymphocytes in PB and PLN of normothermic controls (37.1 ± 0.2°C) and WBH-treated mice was significant (* indicates P < .02 and **,P < .03).

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