Stx1-induced changes in platelet ultramorphology.

Platelet aggregates were formed after incubation with 10 pg/mL (A), 100 pg/mL (B), 1 ng/mL (C, D) Stx1. Long pseudopodia were noted (A, B, D), and highly activated platelets flattened and adhered firmly to the glass (E, Stx1 100 pg/mL). Panels F, G, and H show unstimulated platelets that are round, discoid, or elongated and do not aggregate.